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Rekha C Patel Selected Research

eIF-2 Kinase (eIF 2 Kinase)

1/2022DYT-PRKRA Mutation P222L Enhances PACT's Stimulatory Activity on Type I Interferon Induction.
1/2021Regulation of PKR activation and apoptosis during oxidative stress by TRBP phosphorylation.
12/2020Dystonia 16 (DYT16) mutations in PACT cause dysregulated PKR activation and eIF2α signaling leading to a compromised stress response.
1/2018Stress-induced TRBP phosphorylation enhances its interaction with PKR to regulate cellular survival.
9/2015Altered activation of protein kinase PKR and enhanced apoptosis in dystonia cells carrying a mutation in PKR activator protein PACT.

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Rekha C Patel Research Topics

Disease

5Virus Diseases (Viral Diseases)
01/2021 - 08/2002
3Dystonia 16
01/2022 - 11/2019
2Starvation
01/2009 - 08/2002
1Disease Susceptibility (Diathesis)
12/2021
1Porcine Reproductive and Respiratory Syndrome (PRRS)
12/2021
1Movement Disorders (Movement Disorder)
11/2019
1Inflammation (Inflammations)
11/2017
1Infections
01/2017
1Dystonia (Limb Dystonia)
09/2015
1Neuroblastoma
02/2014
1Atherosclerosis
12/2007

Drug/Important Bio-Agent (IBA)

5Proteins (Proteins, Gene)FDA Link
01/2022 - 08/2002
5eIF-2 Kinase (eIF 2 Kinase)IBA
01/2022 - 09/2015
5InterferonsIBA
01/2022 - 01/2017
3Double-Stranded RNA (RNA, Double Stranded)IBA
01/2021 - 01/2018
2RNA (Ribonucleic Acid)IBA
01/2022 - 08/2012
2Antiviral Agents (Antivirals)IBA
12/2021 - 01/2017
2CytokinesIBA
11/2017 - 12/2007
2arseniteIBA
01/2009 - 08/2002
2PeroxidesIBA
01/2009 - 08/2002
1Pattern Recognition ReceptorsIBA
12/2021
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2020
1CaspasesIBA
11/2019
1tat Gene Products (tat Protein)IBA
01/2017
1Phosphotransferases (Kinase)IBA
01/2017
1Viral ProteinsIBA
01/2017
1TunicamycinIBA
02/2014
1E-SelectinIBA
12/2007
1Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
12/2007
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
12/2007